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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CENPA
All Species:
10.91
Human Site:
T21
Identified Species:
17.14
UniProt:
P49450
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49450
NP_001035891.1
140
15991
T21
R
R
R
S
P
S
P
T
P
T
P
G
P
S
R
Chimpanzee
Pan troglodytes
XP_515346
138
15774
T21
R
R
R
S
P
S
P
T
P
G
P
S
R
R
G
Rhesus Macaque
Macaca mulatta
XP_001087306
138
15765
T21
R
R
R
S
P
S
P
T
P
G
P
S
R
R
G
Dog
Lupus familis
XP_532899
135
15196
A21
P
A
S
P
A
P
S
A
P
R
R
G
P
S
L
Cat
Felis silvestris
Mouse
Mus musculus
O35216
134
15491
P21
P
S
S
P
A
P
G
P
S
R
Q
S
S
S
V
Rat
Rattus norvegicus
P84245
136
15309
L21
G
K
A
P
R
K
Q
L
A
T
K
A
A
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509693
121
13998
G25
R
R
R
R
Y
R
P
G
K
Q
V
L
K
E
I
Chicken
Gallus gallus
Q6XXM1
131
15224
P22
P
P
P
A
A
P
P
P
P
P
A
R
P
R
A
Frog
Xenopus laevis
Q569M3
150
17325
S30
L
P
T
T
S
R
T
S
P
R
R
P
H
A
Q
Zebra Danio
Brachydanio rerio
Q803H4
145
16662
S23
R
R
R
S
P
P
A
S
L
P
P
P
A
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02299
136
15370
L21
G
K
A
P
R
K
Q
L
A
T
K
A
A
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10453
136
15323
L21
G
K
A
P
R
K
Q
L
A
T
K
A
A
R
K
Sea Urchin
Strong. purpuratus
P06352
136
15483
L21
G
K
A
P
R
K
Q
L
A
T
K
A
A
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LR02
136
15384
L21
G
K
A
P
R
T
L
L
A
T
K
A
A
R
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7RXR3
155
17319
T27
A
V
P
T
P
K
A
T
P
P
G
R
R
K
S
Conservation
Percent
Protein Identity:
100
98.5
92.8
77.1
N.A.
70
45
N.A.
60
58.5
54.6
55.1
N.A.
44.2
N.A.
44.2
44.2
Protein Similarity:
100
98.5
93.5
83.5
N.A.
80.7
56.4
N.A.
72.8
71.4
67.3
64.8
N.A.
57.1
N.A.
56.4
57.1
P-Site Identity:
100
66.6
66.6
26.6
N.A.
6.6
6.6
N.A.
26.6
20
6.6
40
N.A.
6.6
N.A.
6.6
6.6
P-Site Similarity:
100
66.6
66.6
26.6
N.A.
6.6
20
N.A.
26.6
26.6
33.3
46.6
N.A.
20
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.8
N.A.
47.7
Protein Similarity:
N.A.
N.A.
N.A.
58.5
N.A.
61.9
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
34
7
20
0
14
7
34
0
7
34
40
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
34
0
0
0
0
0
7
7
0
14
7
14
0
7
14
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% I
% Lys:
0
34
0
0
0
34
0
0
7
0
34
0
7
7
34
% K
% Leu:
7
0
0
0
0
0
7
34
7
0
0
7
0
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
20
14
14
47
34
27
34
14
47
20
27
14
20
0
0
% P
% Gln:
0
0
0
0
0
0
27
0
0
7
7
0
0
0
7
% Q
% Arg:
34
34
34
7
34
14
0
0
0
20
14
14
20
54
7
% R
% Ser:
0
7
14
27
7
20
7
14
7
0
0
20
7
20
14
% S
% Thr:
0
0
7
14
0
7
7
27
0
40
0
0
0
0
0
% T
% Val:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _